Articles Tagged: cannabinoids

The Magic of CBD Shows Exactly How Inhumane the Drug Laws Really Are

January 27th, 2014 | By

weedpic1

Sanjay Gupta’s CNN documentary has been doing the rounds on YouTube, and just in case if you haven’t seen it, I will summarise – a young girl with a severe form of epilsepy is apparently completely cured by taking cannabis oil, which is high in CBD, one of the many cannabinoids in the cannabis plant. It’s transformative and has to be seen to be believed – here’s the link.

This video has really put a cat amongst the pigeons.

According to High Times:

“Lawmakers in Florida, Pennsylvania, Alabama, and Kentucky who had introduced medical marijuana bills in the past are now abandoning those plans and introducing bills that only legalize “Alepsia”-style medical marijuana”

 Ignorant lawmakers appear to be once again putting stigma before science, by changing medical marijuana bills to only allow CBD medicine. This really is a dangerous and stupid step in totally the wrong direction.

“You can’t get high on it, and it has no street value,”

Apparently. This is what a former state trooper said to the Huntsville Times recently.  I would say it has enormous street value.

Even Republican Senator Paul Sanford has stated that:

“If my child was having 300 seizures a month and there was something I could give them that would cut it down to four, by golly, this gentleman would be making sure I got it,” Sen. Sanford told the Huntsville Times following a forum Tuesday night. “And I’ll be frank: If it meant I had to break the law, I would break the law so I wouldn’t have to watch my infant child go through something like that. If that makes me a bad person, so be it. I think it would make me a great parent, to be honest.”

which leads us to:

“I’m not asking for the legalization of marijuana, whether medically or recreationally,”

Dalton, a parent of a child with Dravet sundrome told lawmakers.

 “What I’m asking you to consider is that CBD oil as a marijuana derivative should be considered much in the same way we use morphine, which is derived from opium.”

Don’t get me wrong – it’s life changing for the kids who are suffering now that may soon be able to get treated – of course.  But there is much more to do than simply allow CBD-based medicines.  There are many other important cannabinoids in the cannabis plant:

CBDA which reduces inflammation and inhibits the growth of cancer cells.

CBG which helps with sleep, promotes the growth of bones, slows bacterial growth and inhibits the growth of cancer cells.

THCV which reduces convulsions and seizures as well as many others.

That’s not to mention the relief THC gives chemotherapy patients, as well as its ability to stop muscle spasms.  You get the picture. We need all of it.

 

CANNABINOID-HUMAN-EFFECTS1

 

 

The sum is greater than the individual parts here, according to the scientists.

In a recent chat I had with Dr Bob Melamede, he happened to address this matter directly:

 “the whole is greater than the sum of the parts, and when you take a cannabis extract versus a pure compound of THC or something else, the extract has always been shown to be more effective. Because the whole is greater than the sum of the parts and there are so many different cannabinoids and other biologically active materials – flavonoids, isoflavonoids, terpenes etc that are in the cannabis plant”

It’s also the users who report that they prefer using the whole plant to extracted versions of THC every time. It’s much easier to dose with a smoke. Popping pills you can’t control the does as easily, and if you get it wrong, it can last for hours.

Removing the THC completely renders the medicine useless to people suffering from AIDS, Cancer, Crohn’s and others. Why would you want to do that? So that prohibitionists can say they are doing the right thing, even if it is completely the wrong thing?

Meanwhile British firm GW pharmaceuticals, who secretly grow warehouses full of cannabis hidden away deep in the English countryside, have got FDA approval to start testing their cannabis extract (which they are calling Epidiolex) and permission to treat 125 epileptic children in the US.

This is cannabis!

CBD is also hitting the headlines in the UK. It’s clear that parents who hear about this effective medicine for severe forms of epilepsy would demand it for their children – wouldn’t you?

Remember – the experiment is not legalisation. The experiment has been prohibition, and it has been an utter failure and cost many their lives.

It has stopped genuine medicine getting to people who need it, and it has been a catalyst for racist police officers to be more racist, amongst many other tragedies.

Holistic Biochemistry of Cannabinoids, by Dr Robert Melamede

January 20th, 2014 | By

I always had my suspicions that cannabis was a super plant, but never in my wildest dreams did I think that it could be responsible for regulating most of the body’s essential processes.  Over to Dr Bob:

“Endocannabinoids are the oil of life. And what they do is minimise. It’s friction we’re talking about. Biochemical friction essentially and what we’d like to do is minimise the consequences, essentially, we don’t want ourselves wearing out. So we need to oil ourselves appropriately, and our bodies try to do that, but there is a direction to our imbalance because even though we’re all unique and we’re all different, we all share a certain characteristic. We’re all getting older and that age is attributable to the accumulated damages that are occurring from that friction and we’ll elaborate on that a little more because as was pointed out by Dr Mephlam, these things have constructive roles as well, they are part of signalling mechanisms.

So free radicals act as chemical messengers they allow us to realise there is an imbalance, and when I say us, I mean at a chemical level between ourselves, between our organs and between us as individuals, formations in our societies, how we fix things.

But certainly on a chemical level, free radicals tell us that something is wrong, lets try to fix it. But alternatively they say something’s wrong, lets kill it, because we don’t want, for example, genetically damaged cells in us. If we can’t fix those genetically damaged cells, then we have mechanisms to do that – dna repair mechanisms – then we get rid of those cells because these are the cells that go on to become cancer.

Is marijuana the ultimate holistic medicine if it is coordinating and balancing all of these different organised entities within our body. Or is it the devil’s weed as others would have us believe?

So we are seeing it working on a sub cellular level. We see that leading up to consciousness demean by transcending scales and how its effect on consciousness has an impact on society. This is why cannabinoids have such a unique evolutionary role because they are transcending like this. So cannabinoids regulate cardiovascular health and this is all work sponsored by the NIH and  researchers all around the world. This is coming out of peer reviewed journals.  I don’t talk about my research as since I became chairman of the biology department. That’s when I shifted to cannabinoid research and it goes very very slowly when you have to waste all your time being chairman.

So cannabinoids regulate cardiovascular health and what you see here is when you have a heart attack blocking oxygen and eventually the oxygen re flows and you have a ischemia reperfusion that generates injury. That injury is free radical associated. Here what you see is that you reduce the cell death in your heart through the endocannabinoid system, so presumably exocannabinoids of various forms will have similar effects.

..Dealing with the heart, with arrhythmia and cell death, and in both cases, the cannabinoids prevent cell death and prevent arrhythmia which are fundamental problems when you have cardiovascular disease.

..It’s regulating the digestion system, so we see that the pharmacological modulation of the endocannabinoid system can provide new therapeutics for a number of diseases. Things like gastro intestinal disease, paralytic ileus, chrons disease, irritable bowel syndrome and a whole variety of digestive system related illnesses where people who are using cannabinoids know it works. This is the foundation for it. It’s this balancing act again of trying to restore biochemical health, essentially.

Cannabinoids have a profound effect on the nervous system. The key component here of this is even if these studies aren’t as positive as many expect them to be, that we are only just beginning to appreciate the huge therapeutic potential of this family of compounds is clear.

For multiple sclerosis, for pain, for spasticity, for a whole variety of neurologically related imbalances, the endocannabinoid system is how your body is trying to fix you, and if you’re not being fixed, that means you need more, so the ideal medicine is often not the little purple pill that you see on TV or any of the variety of things. In my mind, the first choice medicine should be cannabinoids when there is an indication for it because they are mimicking what your body is doing.”

More in this video: